Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL5154976 | 0.94 | USP2 (0.58) | USP2KDM4ELMNAALDH1A1CYP1A2 | |
| Methyl Alcohol SCHEMBL27869223 | 0.91 | USP2 (0.54) | USP2KDM4ELMNAALDH1A1CYP1A2 | |
| Ethane SCHEMBL2303498 | 0.91 | USP2 (0.54) | USP2KDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL1638881 | 0.91 | LMNA (0.53) | USP2KDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL30754 | 0.91 | LMNA (0.53) | USP2KDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL1709058 | 0.89 | USP2 (0.54) | USP2KDM4ELMNAALDH1A1CYP1A2 | |
| Alcohol SCHEMBL12475875 | 0.89 | USP2 (0.54) | USP2KDM4ELMNAALDH1A1CYP1A2 | |
| Isobutane SCHEMBL27997158 | 0.88 | USP2 (0.52) | USP2KDM4ELMNAALDH1A1CYP1A2 | |
| Isopropyl Alcohol SCHEMBL7787253 | 0.88 | USP2 (0.52) | USP2KDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL25238278 | 0.88 | LMNA (0.50) | USP2KDM4ELMNAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011124146-A1 | YEAST HAVING IMPROVED ETHANOL YIELD | TIANJIN UNIVERSITY (CN) | 2011-10-13 | — | — | WO | disclosed |