SCHEMBL1709058

SCHEMBL1709058

CCC(O)COCC(O)CO

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.54
KDM4E B2RXH2 3/20 0.44
LMNA P02545 4/20 0.40
ALDH1A1 P00352 1/20 0.40
DUSP3 P51452 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD17B10 Q99714 1/20 0.37
CYP1A2 P05177 2/20 0.35
AGTR1 P30556 1/20 0.35
TSHR P16473 2/20 0.33
HTT P42858 1/20 0.33
MAPK1 P28482 1/20 0.33
THRB P10828 1/20 0.33
DGKA P23743 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26210276 0.97 USP2 (0.52) USP2KDM4ELMNAALDH1A1DUSP3
SCHEMBL7606705 0.97 USP2 (0.52) USP2KDM4ELMNAALDH1A1DUSP3
SCHEMBL13398700 0.90 USP2 (0.50) USP2KDM4ELMNAALDH1A1DUSP3
Propane SCHEMBL5154976 0.89 USP2 (0.58) USP2KDM4ELMNAALDH1A1DUSP3
Alcohol SCHEMBL2553945 0.89 USP2 (0.58) USP2KDM4ELMNAALDH1A1DUSP3
SCHEMBL20438581 0.89 USP2 (0.50) USP2KDM4ELMNAALDH1A1DUSP3
SCHEMBL325805 0.89 KDM4E (0.52) USP2KDM4EHSD17B10TSHRHTT
SCHEMBL13024121 0.87 USP2 (0.48) USP2KDM4ELMNAALDH1A1DUSP3
SCHEMBL20438574 0.87 USP2 (0.48) USP2KDM4ELMNAALDH1A1DUSP3
SCHEMBL20438570 0.87 USP2 (0.44) USP2KDM4ELMNAALDH1A1DUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230372500-A1 MULTI-ARM POLYMER CONJUGATES OF TLR AGONIST COMPOUNDS AND RELATED IMMUNOTHERAPEUTIC TREATMENT METHODS NEKTAR THERAPEUTICS (US) 2023-11-23 US disclosed
WO-2023219973-A1 LOW MOLECULAR WEIGHT DISPERSANTS CHEVRON ORONITE COMPANY LLC (US) 2023-11-16 WO disclosed
WO-2023219975-A1 LUBRICANT ADDITIVES CHEVRON ORONITE COMPANY LLC (US) 2023-11-16 WO disclosed
US-11813241-B2 Multi-arm polymeric prodrug conjugates of taxane-based compounds NEKTAR THERAPEUTICS (US) 2023-11-14 US disclosed
US-11744898-B2 Multi-arm polymer conjugates of TLR agonist compounds and related immunotherapeutic treatment methods NEKTAR THERAPEUTICS (US) 2023-09-05 US disclosed
US-11744925-B2 Coatings MICROVENTION, INC. (US) 2023-09-05 US disclosed
WO-2023275241-A1 CROSSLINKED HYALURONIC ACID COMPOSITION WITH LOCAL ANESTHETICS BIOPOLIMERI S.R.L. (IT) 2023-01-05 WO disclosed
EP-3331491-B1 POLYMERS DERIVED FROM AMINO-FUNCTIONAL VINYL ALCOHOL ETHERS AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2022-03-23 EP disclosed
US-9907854-B2 Crosslinking reagents, macromolecules, therapeutic bioconjugates, and synthetic methods thereof CellMosaic, Inc. (US) 2018-03-06 US disclosed
US-20180043028-A1 POLYMER-SUNITINIB CONJUGATES NEKTAR THERAPEUTICS 2018-02-15 US disclosed
US-8182841-B2 Amniotic membrane preparations and purified compositions and anti-inflammation methods TISSUE TECH, INC. (US) 2012-05-22 US disclosed
US-20120088927-A1 Methods for the Formation of Hydrogels Using Thiosulfonate Compositions and Uses Thereof NEKTAR THERAPEUTICS (US) 2012-04-12 US disclosed
US-8097695-B2 Methods for the formation of hydrogels using thiosulfonate compositions and uses thereof NEKTAR THERAPEUTICS (US) 2012-01-17 US disclosed
US-20100216915-A1 Levulinic acid ester derivatives as reactive plasticizers and coalescent solvents ARCHER-DANIELS-MIDLAND COMPANY (US) 2010-08-26 US disclosed
US-7659234-B2 Personal care compositions containing quaternary ammonium trihydroxy substituted dipropyl ether CONOPCO, INC. (US) 2010-02-09 US disclosed
US-20100004424-A1 Methods for the Formation of Hydrogels Using Thiosulfonate Compositions and Uses Thereof NEKTAR THERAPEUTICS (US) 2010-01-07 US disclosed
US-20070231401-A1 Amniotic membrane preparations and purified compositions and anti-inflammation methods BIO-TISSUE, INC. (US) 2007-10-04 US disclosed
US-20070212324-A1 PERSONAL CARE COMPOSITIONS CONTAINING QUATERNARY AMMONIUM TRIHYDROXY SUBSTITUTED DIPROPYL ETHER CONOPCO, INC., D/B/A UNILEVER (US) 2007-09-13 US disclosed
US-6764979-B2 INCREASING PENETRATION OF IOXYNIL OR DERIVATIVE THEREOF INTO LEAVES OF PLANT BY CONTACTING WITH COMPOSITION COMPRISING WATER, IOXYNIL COMPOUND, AND ALKOXYLATED ALCOHOLS OR ALKOXYLATED FATTY ACID ESTERS COGNIS DEUTSCHLAND GMBH & CO. KG (DE) 2004-07-20 US disclosed
US-20030158044-A1 Aqueous herbicidal agent COGNIS IP MANAGEMENT GMBH (DE) 2003-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230372500-A1 MULTI-ARM POLYMER CONJUGATES OF TLR AGONIST COMPOUNDS AND RELATED IMMUNOTHERAPEUTIC TREATMENT METHODS TLR7, TLR8, TLR3 USP2 1495/4885KDM4E 2064/4885LMNA 4463/4885
US-11813241-B2 Multi-arm polymeric prodrug conjugates of taxane-based compounds PAICS, FOLR1, FOLR2 USP2 3260/4885KDM4E 4126/4885LMNA 1880/4885
US-20100216915-A1 Levulinic acid ester derivatives as reactive plasticizers and coalescent solvents EPM2A, ALAD, GABRD USP2 2095/4885KDM4E 2014/4885LMNA 908/4885
US-11744898-B2 Multi-arm polymer conjugates of TLR agonist compounds and related immunotherapeutic treatment methods TLR7, TLR8, TLR3 USP2 1658/4885KDM4E 2121/4885LMNA 4373/4885
US-20100004424-A1 Methods for the Formation of Hydrogels Using Thiosulfonate Compositions and Uses Thereof TST, CTH, MPST USP2 884/4885KDM4E 3761/4885LMNA 4748/4885
US-20180043028-A1 POLYMER-SUNITINIB CONJUGATES FLT4, TEK, TIE1 USP2 2764/4885KDM4E 1439/4885LMNA 4325/4885
US-20120088927-A1 Methods for the Formation of Hydrogels Using Thiosulfonate Compositions and Uses Thereof TST, CTH, MPST USP2 884/4885KDM4E 3761/4885LMNA 4748/4885
US-20070212324-A1 PERSONAL CARE COMPOSITIONS CONTAINING QUATERNARY AMMONIUM TRIHYDROXY SUBSTITUTED DIPROPYL ETHER USP39, USP36, USP47 USP2 146/4885KDM4E 190/4885LMNA 3367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.