SCHEMBL25539508

SCHEMBL25539508

c1ccc(-c2cccc([Si](c3ccccc3)(c3ccccc3)c3cc(-c4ccccc4)c(-n4c5ccccc5c5cc(-c6ccc7c8ccccc8n(-c8ccccc8)c7c6)ccc54)c(-c4ccccc4)c3)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSPO P30536 1/20 0.32
PTGER4 P35408 1/20 0.32
MAPK14 Q16539 1/20 0.31
AVPR1A P37288 1/20 0.30
HDAC4 P56524 1/20 0.30
KMT2A Q03164 1/20 0.30
IL1R1 P14778 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25539518 1.00 KDM4E (0.38) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL25539340 0.97 L3MBTL1 (0.41) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL25539333 0.97 L3MBTL1 (0.41) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL25539510 0.96 KDM4E (0.38) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL25539513 0.96 L3MBTL1 (0.40) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL25539505 0.96 L3MBTL1 (0.42) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL25539383 0.94 KDM4E (0.37) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL25539101 0.94 KDM4E (0.37) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL25539092 0.94 KDM4E (0.37) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL25539380 0.94 KDM4E (0.37) KDM4EATML3MBTL1TSPOPTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159570-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 US disclosed
US-20230159570-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159570-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND CRY1, CYP1A1, NQO1 KDM4E 3633/4885ATM 3960/4885L3MBTL1 1368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.