SCHEMBL2553972

SCHEMBL2553972

Cn1c(N)c(C=O)c(=O)[nH]c1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.46
KMT2A Q03164 3/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
GFER P55789 1/20 0.40
CDK1 P06493 1/20 0.39
TPI1 P60174 1/20 0.39
GAA P10253 3/20 0.36
MAPT P10636 4/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GLA P06280 1/20 0.36
CHRNB2 P17787 1/20 0.36
ADRA1D P25100 1/20 0.36
HTR1E P28566 1/20 0.36
CHRNA3 P32297 1/20 0.36
ADRA1A P35348 1/20 0.36
ADRA1B P35368 1/20 0.36
OPRM1 P35372 1/20 0.36
OPRK1 P41145 1/20 0.36
DAO P14920 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16751121 0.76 KMT2A (0.42) EPHX2KMT2AGAAMAPTDAO
SCHEMBL1546631 0.74 EPHX2 (0.52) EPHX2KMT2ANPC1RAB9AGFER
SCHEMBL15667389 0.72 EPHX2 (0.50) EPHX2KMT2ANPC1RAB9AGFER
SCHEMBL6673604 0.72 EPHX2 (0.42) EPHX2KMT2ANPC1RAB9AGFER
SCHEMBL6013388 0.71 MAPT (0.59) EPHX2KMT2ANPC1RAB9AGFER
SCHEMBL4020746 0.71 EPHX2 (0.45) EPHX2KMT2ANPC1RAB9AGFER
Formic Acid SCHEMBL6687413 0.68 EPHX2 (0.40) EPHX2KMT2ANPC1RAB9AGFER
SCHEMBL15075767 0.68 KDM4E (0.46) EPHX2KMT2ANPC1RAB9AGFER
SCHEMBL16334263 0.68 SMN1; SMN2 (0.66) EPHX2KMT2ANPC1RAB9AGFER
SCHEMBL9412532 0.68 KDM4E (0.51) EPHX2KMT2ANPC1RAB9AGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed
EP-2558577-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2013-02-20 EP disclosed
WO-2011127933-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2011-10-20 WO disclosed