Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | TPI1 | P60174 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673604 | 0.95 | EPHX2 (0.42) | EPHX2KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL9412532 | 0.75 | KDM4E (0.51) | EPHX2KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL10667165 | 0.75 | KDM4E (0.63) | KMT2AALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL15075767 | 0.74 | KDM4E (0.46) | EPHX2KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL6886919 | 0.73 | EPHX2 (0.41) | EPHX2KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL9430532 | 0.73 | KDM4E (0.70) | KMT2AALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL9847038 | 0.71 | ALDH1A1 (0.34) | ALDH1A1CYP2C19LMNAMAPTCHRNB2 | |
| SCHEMBL10699801 | 0.71 | KDM4E (0.68) | KMT2AALDH1A1CYP2C19KDM4EGAA | |
| SCHEMBL15075764 | 0.70 | KDM4E (0.44) | EPHX2KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL17682245 | 0.69 | EPHX2 (0.44) | EPHX2KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463727-A2 | HETEROCYCLIC COMPOUNDS THAT ARE INHIBITORS OF THE ENZYME DPP-IV | NOVO NORDISK A/S (DK) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003024965-A2 | HETEROCYCLIC COMPOUNDS THAT ARE INHIBITORS OF THE ENZYME DPP-IV | NOVO NORDISK A/S (DK) | 2003-03-27 | — | — | WO | disclosed |