Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25872053 | 0.80 | POLB (0.34) | HRH3CYP2D6KCNH2TACR1POLB | |
| SCHEMBL26030107 | 0.79 | KCNH2 (0.34) | DPP4HRH3CYP2D6KCNH2POLB | |
| SCHEMBL25530347 | 0.79 | DPP4 (0.39) | DPP4POLBL3MBTL1 | |
| SCHEMBL24448652 | 0.78 | PIK3CD (0.37) | HRH3CYP2D6KCNH2TACR1POLB | |
| SCHEMBL26546789 | 0.78 | NR1H2 (0.41) | HRH3TACR1 | |
| SCHEMBL25872056 | 0.78 | NR1H2 (0.41) | HRH3TACR1 | |
| SCHEMBL20314875 | 0.75 | JAK3 (0.34) | POLBL3MBTL1 | |
| SCHEMBL22255419 | 0.72 | SMN1; SMN2 (0.38) | DPP4HRH3CYP2D6KCNH2 | |
| SCHEMBL19888198 | 0.71 | HTT (0.40) | HRH3CYP2D6KCNH2 | |
| SCHEMBL24206781 | 0.71 | HTT (0.40) | HRH3CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | DPP4 130/4885HRH3 2165/4885CYP2D6 1521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.