Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | TACR2 | P21452 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TST | Q16762 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006146 | 0.94 | ESR1 (0.53) | ESR1ESR2ADRA2ASLC6A2ALDH1A1 | |
| SCHEMBL9671911 | 0.89 | MEN1 (0.46) | ESR1ADRA2ASLC6A2ALDH1A1ADORA3 | |
| SCHEMBL450038 | 0.86 | ESR1 (0.59) | ESR1ESR2ADRA2ASLC6A2ALDH1A1 | |
| SCHEMBL9553570 | 0.82 | TSHR (0.48) | HSD17B10L3MBTL1KMT2AMEN1 | |
| SCHEMBL9552742 | 0.82 | TSHR (0.48) | HSD17B10L3MBTL1KMT2AMEN1 | |
| SCHEMBL7125488 | 0.80 | OPRK1 (0.42) | ESR1ESR2KDM4ECYP3A4HIF1A | |
| SCHEMBL9552934 | 0.79 | MEN1 (0.43) | ESR1ESR2ADRA2ASLC6A2ALDH1A1 | |
| SCHEMBL19510650 | 0.78 | TAAR1 (0.46) | ALDH1A1TAAR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL4714657 | 0.78 | TAAR1 (0.46) | SLC6A4TAAR1KMT2AMEN1 | |
| SCHEMBL9201471 | 0.78 | TAAR1 (0.46) | ALDH1A1SLC6A4IGF1RALOX15HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8858656-B2 | Method for thermally cleaving organic waste having high molecular weight | NEXXOIL AG (CH) | 2014-10-14 | — | — | US | disclosed |
| US-20130091761-A1 | METHOD FOR THERMALLY CLEAVING ORGANIC WASTE HAVING HIGH MOLECULAR WEIGHT | Hochschule Fur Angewandte Wissenschaften Hamburg (Haw Hamburg) (DE) | 2013-04-18 | — | — | US | disclosed |
| EP-2558550-A2 | METHOD FOR THERMALLY CLEAVING ORGANIC WASTE HAVING HIGH MOLECULAR WEIGHT | NEXXOIL AG (CH) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127881-A2 | METHOD FOR THERMALLY CLEAVING ORGANIC WASTE HAVING HIGH MOLECULAR WEIGHT | Hochschule für Angewandte Wissenschaften Hamburg (HAW Hamburg) (DE) | 2011-10-20 | — | — | WO | disclosed |
| CN-1590358-A | Process for preparing calcium carboxylate | SOLUTIA INC (US) | 2005-03-09 | — | — | CN | disclosed |
| EP-0629624-B1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-1267874-A2 | THERAPEUTIC USES OF PPAR MEDIATORS | Aventis Pharma Deutschland GmbH (DE) | 2003-01-02 | — | — | EP | disclosed |
| US-6376512-B1 | FOR TREATING PHYSIOLOGICAL CONDITION IN PATIENT WHEREIN SAID CONDITION IS ASSOCIATED WITH A PHYSIOLOGICALLY DETRIMENTAL LEVELS OF INSULIN, GLUCOSE, FREE FATTY ACIDS, OR TRIGLYCERIDES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-23 | — | — | US | disclosed |
| CN-1073078-C | Process for producing carboxylic acid | DAICEL CHEM (JP) | 2001-10-17 | — | — | CN | disclosed |
| WO-2001066098-A2 | THERAPEUTIC USES OF PPAR MEDIATORS | AVENTIS PHARMA DEUTSCHLAND GMBH | 2001-09-13 | — | — | WO | disclosed |
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5591862-A | ANTILIPEMICS, TREATING DIABETES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| CN-1124246-A | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-06-12 | — | — | CN | disclosed |
| EP-0629624-A1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-21 | — | — | EP | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |
| US-5059610-A | QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-10-22 | — | — | US | disclosed |
| US-4920132-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |
| WO-1989004305-A1 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-05-18 | — | — | WO | disclosed |