Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | TACR2 | P21452 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SHBG | P04278 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | TST | Q16762 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554097 | 0.94 | ESR1 (0.54) | ESR1ADRA2ASLC6A2ALDH1A1ADORA3 | |
| SCHEMBL9552934 | 0.87 | MEN1 (0.43) | ESR1ADRA2ASLC6A2ALDH1A1ADORA3 | |
| SCHEMBL450038 | 0.85 | ESR1 (0.59) | ESR1ADRA2ASLC6A2ALDH1A1ADORA3 | |
| SCHEMBL9553062 | 0.83 | TSHR (0.52) | ALDH1A1HIF1AHSD17B10MEN1KMT2A | |
| SCHEMBL9553703 | 0.83 | TSHR (0.52) | ALDH1A1HIF1AHSD17B10MEN1KMT2A | |
| SCHEMBL7125488 | 0.82 | OPRK1 (0.42) | ESR1KDM4ECYP3A4HIF1AHSD17B10 | |
| SCHEMBL9671911 | 0.82 | MEN1 (0.46) | ESR1ADRA2ASLC6A2ALDH1A1ADORA3 | |
| SCHEMBL449737 | 0.82 | ESR1 (0.77) | ESR1ADRA2ASLC6A2ALDH1A1ADORA3 | |
| SCHEMBL1447579 | 0.79 | ESR1 (0.77) | ESR1ADRA2ASLC6A2ALDH1A1ADORA3 | |
| SCHEMBL7784766 | 0.79 | ESR1 (0.77) | ESR1ADRA2ASLC6A2ALDH1A1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112041165-B | Additive manufacturing with efficient sintering using photothermal dyes | 株式会社理光 | 2024-01-09 | — | — | CN | disclosed |
| CN-112041165-A | Additive manufacturing using photothermal dyes for high efficiency sintering | 株式会社理光 | 2020-12-04 | — | — | CN | disclosed |
| CN-107129659-B | Method for solid freeform fabrication | 株式会社理光 | 2020-11-24 | — | — | CN | disclosed |
| EP-1267874-A2 | THERAPEUTIC USES OF PPAR MEDIATORS | Aventis Pharma Deutschland GmbH (DE) | 2003-01-02 | — | — | EP | disclosed |
| US-6376512-B1 | FOR TREATING PHYSIOLOGICAL CONDITION IN PATIENT WHEREIN SAID CONDITION IS ASSOCIATED WITH A PHYSIOLOGICALLY DETRIMENTAL LEVELS OF INSULIN, GLUCOSE, FREE FATTY ACIDS, OR TRIGLYCERIDES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-23 | — | — | US | disclosed |
| WO-2001066098-A2 | THERAPEUTIC USES OF PPAR MEDIATORS | AVENTIS PHARMA DEUTSCHLAND GMBH | 2001-09-13 | — | — | WO | disclosed |
| US-5059610-A | QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-10-22 | — | — | US | disclosed |
| US-4920132-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |