SCHEMBL25542887

SCHEMBL25542887

COC(=O)CCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(C)=O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ALB P02768 3/20 0.58
▸ FOLH1 Q04609 2/20 0.51
▸ NOD1 Q9Y239 2/20 0.50
▸ GLP1R P43220 8/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ EPHX2 P34913 1/20 0.44
▸ SIRT6 Q8N6T7 1/20 0.43
▸ SIRT1 Q96EB6 1/20 0.43
▸ FNTA P49354 1/20 0.41
▸ FNTB P49356 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25542854 0.90 FOLH1 (0.58) ALBFOLH1NOD1GLP1REPHX2
SCHEMBL23451113 0.89 FOLH1 (0.63) ALBFOLH1NOD1GLP1RSMN1; SMN2
SCHEMBL25542879 0.86 NOD1 (0.65) ALBFOLH1NOD1GLP1REPHX2
SCHEMBL13286041 0.83 ALB (0.62) ALBFOLH1NOD1GLP1RSMN1; SMN2
SCHEMBL29617648 0.83 NOD1 (0.51) ALBFOLH1NOD1GLP1REPHX2
SCHEMBL13335144 0.82 FOLH1 (0.55) FOLH1EPHX2
SCHEMBL13236367 0.82 ALB (0.60) ALBFOLH1NOD1GLP1RSMN1; SMN2
SCHEMBL25548851 0.81 FOLH1 (0.60) ALBFOLH1NOD1GLP1RSMN1; SMN2
SCHEMBL14073945 0.80 KDM4E (0.57) EPHX2
SCHEMBL13376980 0.80 RECQL (0.61) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230158150-A1 COMPOUND COMPRISING A NUCLEIC ACID AND A HALF-LIFE EXTENSION MOTIF NOVARTIS AG (CH) 2023-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158150-A1 COMPOUND COMPRISING A NUCLEIC ACID AND A HALF-LIFE EXTENSION MOTIF NSUN2, NSUN3, POLM ALB 2473/4885FOLH1 677/4885NOD1 1668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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