SCHEMBL25544140

SCHEMBL25544140

Cc1ccc(CNP(=O)(OCOC(=O)C(C)(C)C)C2CCCN(O)C2=O)c(F)c1

nearest known ligand 0.69

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ENO1 P06733 4/20 0.69
CHRM3 P20309 12/20 0.33
PDE10A Q9Y233 1/20 0.32
EGFR P00533 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
KLKB1 P03952 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22266119 0.92 ENO1 (0.70) ENO1CHRM3ALDH1A1TDP1
SCHEMBL23884968 0.89 ENO1 (0.77) ENO1CHRM3ALDH1A1TDP1
SCHEMBL25544138 0.86 ENO1 (0.84) ENO1ALDH1A1
SCHEMBL25544139 0.85 ENO1 (0.74) ENO1CHRM3ALDH1A1
SCHEMBL22266134 0.85 ENO1 (0.76) ENO1CHRM3ALDH1A1
SCHEMBL25544137 0.85 ENO1 (0.82) ENO1CHRM3
SCHEMBL22266063 0.84 ENO1 (0.76) ENO1CHRM3ALDH1A1TDP1
SCHEMBL22265938 0.84 ENO1 (0.83) ENO1CHRM3ALDH1A1
SCHEMBL22266129 0.82 ENO1 (0.81) ENO1CHRM3
SCHEMBL22275838 0.82 ENO1 (1.00) ENO1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167142-A1 METHODS FOR THE MONO-AMIDATION OF PHOSPHATES AND PHOSPHONATES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167142-A1 METHODS FOR THE MONO-AMIDATION OF PHOSPHATES AND PHOSPHONATES PHPT1, PPIP5K2, PNP ENO1 867/4885CHRM3 3971/4885PDE10A 269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.