Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14740400 | 0.76 | MAPT (0.56) | ALDH1A1POLBMAPTSMN1; SMN2MEN1 | |
| SCHEMBL1040562 | 0.75 | MAPT (0.76) | ALDH1A1POLBMAPTSMN1; SMN2MEN1 | |
| SCHEMBL6378907 | 0.71 | KMT2A (0.43) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL14750964 | 0.70 | MAPT (0.51) | ALDH1A1POLBMAPTSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL27940296 | 0.70 | MAPT (0.67) | ALDH1A1POLBMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9941840 | 0.70 | MAPT (0.67) | ALDH1A1POLBMAPTSMN1; SMN2MEN1 | |
| SCHEMBL2840091 | 0.70 | HTR2A (0.58) | ALDH1A1POLBMAPTSMN1; SMN2MEN1 | |
| SCHEMBL15306501 | 0.70 | KMT2A (1.00) | ALDH1A1POLBMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11661115 | 0.69 | KMT2A (0.48) | ALDH1A1POLBMAPTSMN1; SMN2MEN1 | |
| SCHEMBL1099886 | 0.69 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011127333-A2 | COMPOUNDS FOR TREATING DISEASE, FOR ADMINISTERING, AND FOR PHARMACEUTICAL COMPOSITIONS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2011-10-13 | — | — | WO | disclosed |