SCHEMBL25545471

SCHEMBL25545471

CCSc1nccn1C1CCCC1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.52
TP53 P04637 3/20 0.49
THRB P10828 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.39
ATM Q13315 1/20 0.33
HPGD P15428 1/20 0.33
ALDH1A1 P00352 2/20 0.33
GAA P10253 1/20 0.33
TSHR P16473 1/20 0.33
RECQL P46063 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25545519 0.80 LMNA (0.52) LMNATP53THRBL3MBTL1ATM
SCHEMBL25545477 0.74 L3MBTL1 (0.69) LMNATP53THRBL3MBTL1ATM
SCHEMBL28391787 0.72 F10 (0.39) LMNATP53THRBALDH1A1KMT2A
SCHEMBL18250691 0.71 KDM4E (0.38) LMNATP53THRBALDH1A1MEN1
SCHEMBL11015922 0.69 KDM4E (0.40) LMNATHRBL3MBTL1GAA
SCHEMBL4964108 0.69 KDM4E (0.40) LMNATHRBL3MBTL1GAA
SCHEMBL13416227 0.69
SCHEMBL19064265 0.69
SCHEMBL15543652 0.67 LMNA (0.37) LMNATP53THRBHPGDALDH1A1
SCHEMBL18250732 0.67 F10 (0.37) LMNATP53THRBALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023081967-A1 COMPOUNDS AND USES THEREFOR THE UNIVERSITY OF WESTERN AUSTRALIA (AU) 2023-05-19 WO disclosed