Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 4/20 | 0.31 |
| ▸ | NOS2 | P35228 | 4/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
| ▸ | TGM1 | P22735 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18414246 | 0.77 | MAPT (0.36) | NOS1MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL23012401 | 0.75 | TSHR (0.34) | KDM4EMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL16547469 | 0.73 | PDE10A (0.42) | TDO2PDE10ANOS1KDM4EMAPT | |
| Ammonia Solution, Strong SCHEMBL29148764 | 0.71 | PDE10A (0.39) | TDO2PDE10ANOS1KDM4EMAPT | |
| SCHEMBL12528560 | 0.70 | HSD11B1 (0.42) | TDO2PDE10AKDM4EMAPTMAPK1 | |
| SCHEMBL1954358 | 0.69 | TDO2 (0.49) | TDO2NOS1KDM4EMAPTMAPK1 | |
| SCHEMBL11962635 | 0.69 | TDO2 (0.49) | TDO2NOS1KDM4EMAPTMAPK1 | |
| SCHEMBL27020084 | 0.69 | TDO2 (0.41) | TDO2PDE10ANOS1KDM4EMAPT | |
| SCHEMBL15722177 | 0.69 | MAPT (0.46) | TDO2PDE10AKDM4EMAPTMAPK1 | |
| SCHEMBL2547017 | 0.69 | ADORA2A (0.53) | TDO2PDE10AKDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3325486-B1 | POLYNITROGEN COMPOUNDS AND USES THEREOF AS FLUORESCENT CHROMOPHORES | UNIV ORLEANS (FR) | 2023-05-24 | — | — | EP | disclosed |