Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 5/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28879354 | 0.79 | PYCR1 (0.44) | PYCR1CNR2IDO1CYP2C19CYP1A2 | |
| SCHEMBL15603380 | 0.79 | TSHR (0.58) | PYCR1TAAR1 | |
| SCHEMBL16312619 | 0.75 | PYCR1 (0.65) | PYCR1IDO1CYP2C19HRH3CYP1A2 | |
| SCHEMBL12374 | 0.75 | HRH3 (0.67) | PYCR1IDO1CYP2C19HRH3HSP90AA1 | |
| Phosphine SCHEMBL25337730 | 0.73 | HRH3 (0.64) | PYCR1IDO1CYP2C19HRH3HSP90AA1 | |
| Bromide SCHEMBL3671914 | 0.73 | HRH3 (0.64) | PYCR1IDO1CYP2C19HRH3HSP90AA1 | |
| Hydrochloric Acid SCHEMBL28688142 | 0.73 | HRH3 (0.64) | PYCR1IDO1CYP2C19HRH3HSP90AA1 | |
| Bromide SCHEMBL3977215 | 0.73 | HRH3 (0.64) | PYCR1IDO1CYP2C19HRH3HSP90AA1 | |
| SCHEMBL29268397 | 0.72 | PYCR1 (0.39) | PYCR1CNR2IDO1CYP2C19TAS2R14 | |
| SCHEMBL19513365 | 0.72 | HSP90AA1 (0.49) | PYCR1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159469-A1 | NOVEL PHTHALAZINE DERIVATIVE HAVING ECTONUCLOEOTIDE PYROPHOSPHATASE/PHOSPHODIESTE RASE INHIBITORY ACTIVITY, AND USE THEREOF | TXINNO BIOSCIENCE INC. (KR) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159469-A1 | NOVEL PHTHALAZINE DERIVATIVE HAVING ECTONUCLOEOTIDE PYROPHOSPHATASE/PHOSPHODIESTE RASE INHIBITORY ACTIVITY, AND USE THEREOF | ENPP1, ENPP3, PPA1 | PYCR1 2036/4885CNR2 3560/4885IDO1 3472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.