Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRD2 | P25440 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25546322 | 0.88 | NOTUM (0.43) | NOTUMKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL25546032 | 0.85 | KMT2A (0.47) | NOTUMKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL25545940 | 0.85 | NOTUM (0.44) | NOTUMKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL25546356 | 0.78 | KDM4E (0.46) | KMT2AKDM4EALDH1A1HPGDFBP1 | |
| SCHEMBL25546406 | 0.78 | CHEK1 (0.40) | NOTUMKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL25546513 | 0.77 | SMN1; SMN2 (0.47) | KMT2AKDM4EFBP1SMN1; SMN2MEN1 | |
| SCHEMBL25546355 | 0.72 | FBP1 (0.42) | KMT2AKDM4EFBP1SMN1; SMN2DCK | |
| SCHEMBL25546364 | 0.72 | FBP1 (0.45) | KMT2AKDM4EHPGDFBP1SMN1; SMN2 | |
| SCHEMBL25545933 | 0.72 | TDP1 (0.44) | KDM4EALDH1A1HPGDFBP1SMN1; SMN2 | |
| SCHEMBL25546361 | 0.71 | FBP1 (0.43) | KMT2AFBP1TSHRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | EIF4E, EIF4EBP1, EIF4A1 | NOTUM 3220/4885KMT2A 1931/4885KDM4E 710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.