Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.44 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 3/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557582 | 0.87 | GPR119 (0.47) | GPR119SLC5A7HRH3CYP2D6 | |
| SCHEMBL2550758 | 0.83 | GPR119 (0.65) | GPR119 | |
| SCHEMBL2575142 | 0.83 | GPR119 (0.65) | GPR119 | |
| SCHEMBL14634535 | 0.81 | GPR119 (0.45) | GPR119SCDFPR2PROKR1HRH3 | |
| SCHEMBL2556367 | 0.81 | GPR119 (0.45) | GPR119SCDFPR2PROKR1HRH3 | |
| SCHEMBL14634556 | 0.81 | GPR119 (0.59) | GPR119 | |
| SCHEMBL14634557 | 0.81 | GPR119 (0.59) | GPR119 | |
| SCHEMBL14634558 | 0.81 | GPR119 (0.59) | GPR119 | |
| SCHEMBL12282975 | 0.76 | GPR119 (0.73) | GPR119 | |
| SCHEMBL2553366 | 0.76 | GPR119 (0.73) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556056-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011127051-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2011-10-13 | — | — | WO | disclosed |