Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2550758 | 1.00 | GPR119 (0.65) | GPR119 | |
| SCHEMBL2553141 | 0.84 | GPR119 (0.50) | GPR119 | |
| SCHEMBL2554645 | 0.83 | GPR119 (0.44) | GPR119 | |
| SCHEMBL12282718 | 0.83 | GPR119 (0.81) | GPR119 | |
| SCHEMBL12283354 | 0.83 | GPR119 (0.81) | GPR119 | |
| SCHEMBL2552149 | 0.83 | GPR119 (0.81) | GPR119 | |
| SCHEMBL14634425 | 0.83 | GPR119 (0.81) | GPR119 | |
| SCHEMBL14634226 | 0.83 | GPR119 (0.81) | GPR119 | |
| SCHEMBL2552148 | 0.83 | GPR119 (0.81) | GPR119 | |
| SCHEMBL14634288 | 0.82 | GPR119 (0.69) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556056-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011127051-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2011-10-13 | — | — | WO | disclosed |