Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL839348 | 0.85 | NAMPT (0.66) | PTPRCPTPN1NAMPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL25547335 | 0.84 | NAMPT (0.62) | PTPRCPTPN1NAMPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL418094 | 0.83 | MEN1 (0.60) | PTPRCPTPN1NAMPTPARP1SMN1; SMN2 | |
| SCHEMBL7649333 | 0.83 | PTPRC (0.60) | PTPRCPTPN1NAMPTPARP1SMN1; SMN2 | |
| SCHEMBL13316189 | 0.83 | MAPK1 (0.67) | PTPRCPTPN1NAMPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2349758 | 0.82 | NAMPT (0.70) | PTPRCPTPN1NAMPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL964881 | 0.80 | MEN1 (0.78) | PTPRCPTPN1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL3576760 | 0.79 | KMT2A (0.68) | PTPRCPTPN1ALDH1A1MAPTKMT2A | |
| SCHEMBL3857194 | 0.78 | MAPT (0.58) | PTPRCPTPN1NAMPTPARP1ALDH1A1 | |
| SCHEMBL4092498 | 0.78 | KMT2A (0.60) | PTPRCPTPN1SMN1; SMN2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081967-A1 | COMPOUNDS AND USES THEREFOR | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2023-05-19 | — | — | WO | disclosed |