Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.66 |
| ▸ | PTPRC | P08575 | 1/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2349758 | 0.96 | NAMPT (0.70) | NAMPTPTPRCPTPN1ALDH1A1RAB9A | |
| SCHEMBL1931512 | 0.92 | NAMPT (0.65) | NAMPTPTPRCPTPN1ALDH1A1RAB9A | |
| SCHEMBL10600708 | 0.89 | NAMPT (0.55) | NAMPTPTPRCPTPN1ALDH1A1RAB9A | |
| SCHEMBL10598307 | 0.89 | KMT2A (0.64) | NAMPTPTPRCPTPN1ALDH1A1RAB9A | |
| SCHEMBL19932361 | 0.89 | NAMPT (0.62) | NAMPTPTPRCPTPN1ALDH1A1RAB9A | |
| SCHEMBL415057 | 0.89 | NAMPT (0.62) | NAMPTPTPRCPTPN1ALDH1A1RAB9A | |
| SCHEMBL10598737 | 0.89 | RAB9A (0.56) | NAMPTPTPRCPTPN1ALDH1A1RAB9A | |
| SCHEMBL25547335 | 0.89 | NAMPT (0.62) | NAMPTPTPRCPTPN1ALDH1A1RAB9A | |
| SCHEMBL2003113 | 0.89 | NAMPT (0.62) | NAMPTPTPRCPTPN1ALDH1A1RAB9A | |
| SCHEMBL9125307 | 0.87 | ALDH1A1 (0.65) | ALDH1A1RAB9ASMN1; SMN2EPHX2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101356173-A | Novel pyridopyrazines and their use as modulators of kinases | AETERNA ZENTARIS GMBH (DE) | 2009-01-28 | — | — | CN | claimed |
| EP-1957487-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | AEterna Zentaris GmbH (DE) | 2008-08-20 | — | — | EP | claimed |
| US-20070149484-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | ZENTARIS GMBH (DE) | 2007-06-28 | — | — | US | claimed |
| WO-2007054556-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | ÆTERNA ZENTARIS GMBH (DE) | 2007-05-18 | — | — | WO | claimed |
| EP-0678502-B1 | Process for preparing glycoloylanilides | CLARIANT GMBH (DE) | 1999-03-31 | — | — | EP | claimed |
| US-5616799-A | REACTING A CORRESPONDING NITRO COMPOUND WITH A KETONE AND HYDROGEN IN PRESENCE OF A NOBLE METAL CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | claimed |
| EP-0136678-B1 | HEAT SENSITIVE RECORD MATERIAL | HODOGAYA CHEMICAL CO., LTD. (JP) | 1989-09-13 | — | — | EP | claimed |
| US-4539577-A | Heat sensitive record material | HODOGAYA CHEMICAL CO., LTD. (JP) | 1985-09-03 | — | — | US | claimed |
| EP-0136678-A2 | Heat sensitive record material | HODOGAYA CHEMICAL CO., LTD. (JP) | 1985-04-10 | — | — | EP | claimed |
| US-4241154-A | CHELATE COMPOUNDS, COLOR PHOTOGRAPHY | FUJI PHOTO FILM CO., LTD. (JP) | 1980-12-23 | — | — | US | claimed |
| JP-8048661-A | — | — | None | — | — | JP | disclosed |
| WO-2023081967-A1 | COMPOUNDS AND USES THEREFOR | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2023-05-19 | — | — | WO | disclosed |
| US-8846845-B2 | Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices | BEZWADA BIOMEDICAL, LLC (US) | 2014-09-30 | — | — | US | disclosed |
| US-8802892-B2 | Functionalized phenolic compounds and polymers therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2014-08-12 | — | — | US | disclosed |
| US-8664426-B2 | Functionalized amino acids and absorbable polymers therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2014-03-04 | — | — | US | disclosed |
| EP-0156250-A2 | Fluoran compounds | HODOGAYA CHEMICAL CO., LTD. (JP) | 1985-10-02 | — | — | EP | disclosed |
| EP-0155796-A2 | 6-Tetrahydrofurfurylaminofluoran compound useful as a color former | HODOGAYA CHEMICAL CO., LTD. (JP) | 1985-09-25 | — | — | EP | disclosed |
| US-4539289-A | LIGHT SENSITIVE ELEMENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1985-09-03 | — | — | US | disclosed |
| US-4539577-A | Heat sensitive record material | HODOGAYA CHEMICAL CO., LTD. (JP) | 1985-09-03 | — | — | US | disclosed |
| EP-0136678-A2 | Heat sensitive record material | HODOGAYA CHEMICAL CO., LTD. (JP) | 1985-04-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149484-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | MAP4K2, MAP3K15, MAP3K5 | NAMPT 980/4885PTPRC 475/4885PTPN1 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.