Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.70 |
| ▸ | PTPRC | P08575 | 1/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | CETP | P11597 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL839348 | 0.96 | NAMPT (0.66) | NAMPTPTPRCPTPN1RAB9AALDH1A1 | |
| SCHEMBL1931512 | 0.95 | NAMPT (0.65) | NAMPTPTPRCPTPN1RAB9AALDH1A1 | |
| SCHEMBL2003113 | 0.92 | NAMPT (0.62) | NAMPTPTPRCPTPN1RAB9AALDH1A1 | |
| SCHEMBL415057 | 0.92 | NAMPT (0.62) | NAMPTPTPRCPTPN1RAB9AALDH1A1 | |
| SCHEMBL25547335 | 0.92 | NAMPT (0.62) | NAMPTPTPRCPTPN1RAB9AALDH1A1 | |
| SCHEMBL19932361 | 0.92 | NAMPT (0.62) | NAMPTPTPRCPTPN1RAB9AALDH1A1 | |
| SCHEMBL2939045 | 0.89 | RAB9A (0.60) | NAMPTPTPRCPTPN1RAB9AALDH1A1 | |
| SCHEMBL8864260 | 0.89 | SMN1; SMN2 (0.69) | NAMPTPTPRCPTPN1RAB9AALDH1A1 | |
| SCHEMBL19921018 | 0.89 | NAMPT (0.60) | NAMPTPTPRCPTPN1RAB9AALDH1A1 | |
| SCHEMBL12545622 | 0.88 | RAB9A (0.67) | NAMPTPTPRCPTPN1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110313057-A1 | DIFUNCTIONALIZED AROMATIC COMPOUNDS AND POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC (US) | 2011-12-22 | — | — | US | disclosed |
| US-20110313057-A1 | DIFUNCTIONALIZED AROMATIC COMPOUNDS AND POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC (US) | 2011-12-22 | — | — | US | disclosed |
| US-8007526-B2 | Difunctionalized aromatic compounds and polymers therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2011-08-30 | — | — | US | disclosed |
| US-8007526-B2 | Difunctionalized aromatic compounds and polymers therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2011-08-30 | — | — | US | disclosed |
| US-8007526-B2 | Difunctionalized aromatic compounds and polymers therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2011-08-30 | — | — | US | disclosed |
| US-20070129787-A1 | DIFUNCTIONALIZED AROMATIC COMPOUNDS AND POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC (US) | 2007-06-07 | — | — | US | disclosed |
| US-20070129787-A1 | DIFUNCTIONALIZED AROMATIC COMPOUNDS AND POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC (US) | 2007-06-07 | — | — | US | disclosed |
| US-20070129787-A1 | DIFUNCTIONALIZED AROMATIC COMPOUNDS AND POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC (US) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110313057-A1 | DIFUNCTIONALIZED AROMATIC COMPOUNDS AND POLYMERS THEREFROM | AHR, OGFR, OPRM1 | NAMPT 3062/4885PTPRC 1542/4885PTPN1 1284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.