Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL746391 | 0.77 | KDM4E (0.38) | TDP1BTKNPC1CYP1A2KDM4E | |
| SCHEMBL25190263 | 0.77 | RAB9A (0.41) | TDP1NPC1CYP1A2KDM4ESUV39H2 | |
| SCHEMBL20010856 | 0.76 | TBK1 (0.43) | TDP1CYP1A2KDM4ESUV39H2TBK1 | |
| SCHEMBL20428739 | 0.75 | CCR1 (0.42) | BTKKDM4ESUV39H2TBK1IKBKE | |
| SCHEMBL16660952 | 0.75 | IKBKE (0.34) | BTKSUV39H2TBK1IKBKE | |
| SCHEMBL25198156 | 0.75 | HDAC4 (0.35) | BTKCASP3SENP8SENP7SENP6 | |
| SCHEMBL6269678 | 0.74 | P4HTM (0.40) | NPC1CYP1A2RAB9AALDH1A1GAA | |
| SCHEMBL629835 | 0.74 | PIK3CD (0.36) | BTKSUV39H2TBK1IKBKE | |
| SCHEMBL16680799 | 0.73 | PIK3CA (0.37) | BTKSUV39H2TBK1IKBKE | |
| SCHEMBL12208682 | 0.73 | IKBKE (0.41) | TDP1NPC1CYP1A2KDM4ESUV39H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081666-A1 | COMPOUNDS AS CCR2 MODULATORS | ARIA PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |