Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30088694 | 0.99 | ENPP1 (0.52) | ENPP1KDM4ESMN1; SMN2HPGDHTT | |
| SCHEMBL25546465 | 0.85 | ENPP1 (0.49) | ENPP1SMN1; SMN2HPGDHTTMAPT | |
| SCHEMBL24000565 | 0.85 | ENPP1 (0.65) | ENPP1KDM4ESMN1; SMN2HPGDMAPT | |
| SCHEMBL24000572 | 0.85 | ENPP1 (0.71) | ENPP1KDM4ESMN1; SMN2HPGDMAPT | |
| Hydrochloric Acid SCHEMBL31384250 | 0.84 | ENPP1 (0.56) | ENPP1KDM4ESMN1; SMN2HPGDHTT | |
| Hydrochloric Acid SCHEMBL30088859 | 0.84 | ENPP1 (0.64) | ENPP1KDM4ESMN1; SMN2HPGDMAPT | |
| Hydrochloric Acid SCHEMBL30088809 | 0.84 | ENPP1 (0.70) | ENPP1KDM4ESMN1; SMN2HPGDMAPT | |
| SCHEMBL7682628 | 0.81 | MAPT (0.46) | ENPP1KDM4ESMN1; SMN2HPGDHTT | |
| Hydrochloric Acid SCHEMBL28917135 | 0.81 | ENPP1 (0.53) | ENPP1KDM4ESMN1; SMN2HPGDHTT | |
| SCHEMBL24000525 | 0.80 | ENPP1 (0.68) | ENPP1SMN1; SMN2HPGDHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515939-A | Novel phthalazine derivatives having an inhibitory activity on ectonucleotide pyrophosphatase-phosphodiesterase and their use | 谛希诺生物科技有限公司 | 2022-12-23 | — | — | CN | claimed |
| US-20230159469-A1 | NOVEL PHTHALAZINE DERIVATIVE HAVING ECTONUCLOEOTIDE PYROPHOSPHATASE/PHOSPHODIESTE RASE INHIBITORY ACTIVITY, AND USE THEREOF | TXINNO BIOSCIENCE INC. (KR) | 2023-05-25 | — | — | US | disclosed |
| CN-115515939-A | Novel phthalazine derivatives having an inhibitory activity on ectonucleotide pyrophosphatase-phosphodiesterase and their use | 谛希诺生物科技有限公司 | 2022-12-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159469-A1 | NOVEL PHTHALAZINE DERIVATIVE HAVING ECTONUCLOEOTIDE PYROPHOSPHATASE/PHOSPHODIESTE RASE INHIBITORY ACTIVITY, AND USE THEREOF | ENPP1, ENPP3, PPA1 | ENPP1 1/4885KDM4E 2943/4885SMN1; SMN2 3741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.