Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 2/20 | 0.51 |
| ▸ | APEX1 | P27695 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GRK6 | P43250 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | STK17B | O94768 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952111 | 0.84 | HPGD (0.46) | RIPK2ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL13859381 | 0.82 | ALDH1A1 (0.48) | APEX1ALDH1A1GRK6CYP1A2STK17B | |
| SCHEMBL31190735 | 0.80 | KMT2A (0.46) | RIPK2ALDH1A1CYP1A2KMT2AMAPT | |
| SCHEMBL4203420 | 0.80 | RIPK2 (0.43) | RIPK2APEX1ALDH1A1GRK6CYP1A2 | |
| SCHEMBL21450904 | 0.80 | RIPK2 (0.52) | RIPK2APEX1ALDH1A1GRK6CYP1A2 | |
| SCHEMBL2558007 | 0.78 | ALDH1A1 (0.58) | APEX1ALDH1A1CYP1A2KMT2AL3MBTL1 | |
| SCHEMBL6112852 | 0.78 | AR (0.43) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL15331499 | 0.74 | KCNQ3 (0.41) | ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL11770021 | 0.72 | RAB9A (0.56) | RIPK2APEX1ALDH1A1CYP1A2KMT2A | |
| SCHEMBL4859912 | 0.72 | FFAR1 (0.61) | APEX1ALDH1A1STK17BFFAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |