SCHEMBL25548245

SCHEMBL25548245

c1ccc(-c2nc(-c3ccc4c(c3)sc3ccccc34)nc(-c3ccc4ccc5ccc6nn(-c7ccccc7)nc6c5c4c3)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.37
MAPT P10636 3/20 0.31
RAB9A P51151 3/20 0.31
KDM4E B2RXH2 2/20 0.31
NPC1 O15118 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MEN1 O00255 1/20 0.31
STAT1 P42224 1/20 0.31
KMT2A Q03164 1/20 0.31
HPGD P15428 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.30
LMNA P02545 1/20 0.30
RECQL P46063 1/20 0.30
PARP1 P09874 1/20 0.30
ABCG2 Q9UNQ0 1/20 0.30
PIK3CA P42336 1/20 0.30
PI4KA P42356 1/20 0.30
PI4KB Q9UBF8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25548645 0.99 ALOX5 (0.36) ALOX5MAPTRAB9AKDM4ENPC1
SCHEMBL25548225 0.95 ALOX5 (0.35) ALOX5PARP1PIK3CAPI4KAPI4KB
SCHEMBL25548350 0.94 ALOX5 (0.35) ALOX5MAPTRAB9AKDM4ENPC1
SCHEMBL25548216 0.94 ALOX5 (0.37) ALOX5MAPTRAB9AKDM4ENPC1
SCHEMBL25548247 0.93 ALOX5 (0.35) ALOX5MAPTKDM4EALDH1A1MEN1
SCHEMBL25548227 0.93 ALOX5 (0.34) ALOX5ABCG2
SCHEMBL25548226 0.90 ALOX5 (0.36) ALOX5MAPTRAB9AKDM4ENPC1
SCHEMBL25548224 0.90 ALOX5 (0.36) ALOX5MAPTRAB9AKDM4ENPC1
SCHEMBL25548244 0.89 ALOX5 (0.35) ALOX5PARP1
SCHEMBL25548136 0.88 ALOX5 (0.42) ALOX5MAPTRAB9AKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167089-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-06-01 US disclosed
US-20230167089-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-06-01 US disclosed
US-20230157161-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-18 US disclosed
US-20230157161-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-18 US disclosed
US-20230134923-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-04 US disclosed
US-20230134923-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167089-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 ALOX5 977/4885MAPT 940/4885RAB9A 4720/4885
US-20230134923-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 ALOX5 977/4885MAPT 940/4885RAB9A 4720/4885
US-20230157161-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 ALOX5 977/4885MAPT 940/4885RAB9A 4720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.