SCHEMBL25548314

SCHEMBL25548314

CC1(C)c2ccccc2-c2ccc(-c3nc4ccccc4nc3-c3ccc4ccc5ccc6nn(-c7ccccc7)nc6c5c4c3)cc21

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.35
KDM4E B2RXH2 2/20 0.32
HPGD P15428 1/20 0.32
PARP1 P09874 1/20 0.31
ALDH1A1 P00352 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25548316 0.94 ALOX5 (0.35) ALOX5KDM4EHPGDPARP1ALDH1A1
SCHEMBL26411302 0.91 ALOX5 (0.37) ALOX5KDM4EHPGDPARP1ALDH1A1
SCHEMBL25548178 0.90 ALOX5 (0.36) ALOX5KDM4EHPGDALDH1A1
SCHEMBL25548300 0.90 ALOX5 (0.35) ALOX5KDM4EHPGDALDH1A1
SCHEMBL26475991 0.89 ALOX5 (0.35) ALOX5
SCHEMBL26416440 0.89 ALOX5 (0.35) ALOX5PARP1
SCHEMBL25548159 0.89 ALOX5 (0.35) ALOX5
SCHEMBL25609221 0.87 ALOX5 (0.34) ALOX5
SCHEMBL25548167 0.86 ALOX5 (0.34) ALOX5
SCHEMBL25548312 0.84 ALOX5 (0.41) ALOX5KDM4EHPGDPARP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167089-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-06-01 US disclosed
US-20230167089-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-06-01 US disclosed
US-20230157161-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-18 US disclosed
US-20230157161-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-18 US disclosed
US-20230134923-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-04 US disclosed
US-20230134923-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167089-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 ALOX5 977/4885KDM4E 2381/4885HPGD 2664/4885
US-20230134923-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 ALOX5 977/4885KDM4E 2381/4885HPGD 2664/4885
US-20230157161-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 ALOX5 977/4885KDM4E 2381/4885HPGD 2664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.