SCHEMBL25548611

SCHEMBL25548611

c1ccc(-c2cc(-c3ccccc3)cc(-c3cc(-c4ccccc4)nc(-c4ccc5ccc6ccc7nn(-c8ccccc8)nc7c6c5c4)n3)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.38
ALDH1A1 P00352 7/20 0.35
MEN1 O00255 6/20 0.35
KMT2A Q03164 6/20 0.35
MAPT P10636 6/20 0.35
HPGD P15428 6/20 0.35
NTSR1 P30989 1/20 0.35
PTGES O14684 1/20 0.34
KDM4E B2RXH2 6/20 0.34
LMNA P02545 3/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 2/20 0.34
STAT1 P42224 1/20 0.34
GAA P10253 2/20 0.34
POLB P06746 1/20 0.34
TSHR P16473 1/20 0.34
ALOX12 P18054 1/20 0.34
MAPK1 P28482 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25548609 0.97 ALOX5 (0.40) ALOX5ALDH1A1MEN1KMT2AMAPT
SCHEMBL25548146 0.97 ALOX5 (0.40) ALOX5ALDH1A1MEN1KMT2AMAPT
SCHEMBL25548608 0.95 ALOX5 (0.41) ALOX5ALDH1A1MEN1KMT2AMAPT
SCHEMBL25548148 0.94 MEN1 (0.39) ALOX5ALDH1A1MEN1KMT2AMAPT
SCHEMBL25548147 0.93 ALOX5 (0.38) ALOX5ALDH1A1MEN1KMT2AMAPT
SCHEMBL25548139 0.91 ALOX5 (0.39) ALOX5ALDH1A1MEN1KMT2AMAPT
SCHEMBL25548151 0.90 CYP1A1 (0.43) ALOX5ALDH1A1MEN1KMT2AMAPT
SCHEMBL25548137 0.90 ALOX5 (0.41) ALOX5ALDH1A1MEN1KMT2AMAPT
SCHEMBL25548603 0.90 ALOX5 (0.41) ALOX5ALDH1A1MEN1KMT2AMAPT
SCHEMBL25548138 0.90 ALOX5 (0.43) ALOX5ALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167089-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-06-01 US disclosed
US-20230167089-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-06-01 US disclosed
US-20230157161-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-18 US disclosed
US-20230157161-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-18 US disclosed
US-20230134923-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-04 US disclosed
US-20230134923-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167089-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 ALOX5 977/4885ALDH1A1 2385/4885MEN1 1648/4885
US-20230134923-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 ALOX5 977/4885ALDH1A1 2385/4885MEN1 1648/4885
US-20230157161-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 ALOX5 977/4885ALDH1A1 2385/4885MEN1 1648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.