Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 17/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 17/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 17/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16166538 | 0.80 | ADRA1D (0.33) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL2551884 | 0.80 | ADRA1D (0.37) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL17516018 | 0.79 | ADRA1D (0.32) | ADRA1DADRA1AADRA1B | |
| SCHEMBL16166306 | 0.78 | ADRA1D (0.31) | ADRA1DADRA1AADRA1B | |
| SCHEMBL18902664 | 0.78 | ADRA1D (0.40) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL16422047 | 0.78 | ADRA1D (0.35) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL12816693 | 0.76 | — | — | |
| SCHEMBL526254 | 0.74 | NOTUM (0.38) | ADRA1DADRA1AADRA1BHTR1AHTR1B | |
| SCHEMBL16166555 | 0.71 | ADRA1D (0.33) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL16166556 | 0.71 | ADRA1D (0.33) | ADRA1DADRA1AADRA1BADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011124704-A1 | PROCESS FOR PREPARING AN INTERMEDIATE FOR SILODOSIN | RATIOPHARM GMBH (DE) | 2011-10-13 | — | — | WO | disclosed |