Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR1E | P28566 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12505326 | 0.86 | MAPT (0.38) | NOTUMADRA1DADRA1AADRA1BTMEM97 | |
| SCHEMBL525875 | 0.84 | MAPT (0.46) | NOTUMADRA1DTMEM97SIGMAR1SLC6A2 | |
| SCHEMBL16422047 | 0.79 | ADRA1D (0.35) | ADRA1DADRA1AADRA1BHRH1HTR1A | |
| SCHEMBL18902664 | 0.79 | ADRA1D (0.40) | ADRA1DADRA1AADRA1BHRH1HTR1A | |
| SCHEMBL12816693 | 0.79 | — | — | |
| SCHEMBL17516018 | 0.78 | ADRA1D (0.32) | ADRA1DADRA1AADRA1B | |
| SCHEMBL16166306 | 0.77 | ADRA1D (0.31) | ADRA1DADRA1AADRA1B | |
| SCHEMBL12505323 | 0.76 | POLB (0.32) | MAPTMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL526176 | 0.71 | MAPT (0.48) | ADRA1DADRA1AADRA1BNPC1RAB9A | |
| SCHEMBL526097 | 0.71 | NOTUM (0.49) | NOTUMADRA1DTMEM97SIGMAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014186-A1 | PROCESS FOR THE PREPARATION OF SILODOSIN AND ITS NOVEL INTERMEDIATES | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |