SCHEMBL2555005

SCHEMBL2555005

COC(=O)c1ccc(OCCCC2CCN(C(=O)OC(C)C)CC2)cc1C

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 19/20 0.59
FAAH O00519 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2561511 0.90 GPR119 (0.61) GPR119FAAH
SCHEMBL1922356 0.89 GPR119 (0.64) GPR119FAAH
SCHEMBL1295322 0.87 GPR119 (0.61) GPR119
SCHEMBL1839393 0.87 GPR119 (0.46) GPR119
SCHEMBL1839651 0.83 GPR119 (0.44) GPR119
SCHEMBL12283385 0.82 GPR119 (0.42) GPR119
SCHEMBL1575319 0.81 GPR119 (0.66) GPR119FAAH
SCHEMBL1838814 0.81 USP30 (0.42) GPR119
SCHEMBL1575946 0.81 GPR119 (0.68) GPR119FAAH
SCHEMBL1922857 0.81 GPR119 (0.68) GPR119FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011128394-A1 3-SUBSTITUTED 5-(PYRROLIDINE-1-CARBONYL) PYRROLIDINE AND ITS DERIVATIVES FOR USE IN THE TREATMENT OF METABOLIC DISORDERS PROSIDION LIMITED (GB) 2011-10-20 WO disclosed
WO-2011128394-A1 3-SUBSTITUTED 5-(PYRROLIDINE-1-CARBONYL) PYRROLIDINE AND ITS DERIVATIVES FOR USE IN THE TREATMENT OF METABOLIC DISORDERS PROSIDION LIMITED (GB) 2011-10-20 WO disclosed