Dihydroxyacetone

Dihydroxyacetone

SCHEMBL2555249

O=C(CO)CO.O=C(CO)CO

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.40
TDP1 Q9NUW8 1/20 0.36
ACE P12821 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dihydroxyacetone SCHEMBL70 1.00
Dihydroxyacetone SCHEMBL290385 0.95
Dihydroxyacetone SCHEMBL29350199 0.95
Dihydroxyacetone SCHEMBL28636804 0.91
Dihydroxyacetone SCHEMBL17786015 0.91 CA1 (0.46) OR51E2TDP1ACE
Dihydroxyacetone SCHEMBL5542140 0.87 LMNA (0.50) OR51E2TDP1
Dihydroxyacetone SCHEMBL20798012 0.83 KDM4E (0.35) OR51E2TDP1
Dihydroxyacetone SCHEMBL8748109 0.83 CA1 (0.46) OR51E2
Dihydroxyacetone SCHEMBL43279 0.83 KDM4E (0.35) OR51E2TDP1
Dihydroxyacetone SCHEMBL8046819 0.83 FFAR3 (0.54) OR51E2TDP1ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3313994-A1 CARBON-NEUTRAL AND CARBON-POSITIVE PHOTORESPIRATION BYPASS ROUTES SUPPORTING HIGHER PHOTOSYNTHETIC RATE AND YIELD Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2018-05-02 EP disclosed
US-20170340648-A1 Pharmaceutical Compositions Affecting Bioenergetic Processes in a Eukaryotic Biological System and Methods of Treatment JOYCE BIOTECH CORP. (US) 2017-11-30 US disclosed
WO-2017177165-A1 DIESTERS FOR PERSONAL CARE APPLICATIONS DERIVED FROM 1-METHYLHEPTYL ALCOHOL INOLEX INVESTMENT CORPORATION (US) 2017-10-12 WO disclosed
WO-2016207219-A1 CARBON-NEUTRAL AND CARBON-POSITIVE PHOTORESPIRATION BYPASS ROUTES SUPPORTING HIGHER PHOTOSYNTHETIC RATE AND YIELD MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-12-29 WO disclosed
EP-2887929-A2 COMPOUNDS FOR PREVENTING, REDUCING AND/OR ALLEVIATING ITCHY SKIN CONDITION(S) Symrise AG (DE) 2015-07-01 EP disclosed
EP-2555759-A1 LOW ENERGY, COLD PROCESS FORMULATION AID Jeen International Corporation (US) 2013-02-13 EP disclosed
WO-2012143576-A2 COMPOUNDS FOR PREVENTING, REDUCING AND/OR ALLEVIATING ITCHY SKIN CONDITION(S) SYMRISE AG (DE) 2012-10-26 WO disclosed
WO-2011127311-A1 LOW ENERGY, COLD PROCESS FORMULATION AID JEEN INTERNATIONAL CORPORATION (US) 2011-10-13 WO disclosed
EP-1539098-A4 COSMETIC COMPOSITION CONTAINING MICROCRYSTALLINE CELLULOSE FMC CORP (US) 2008-09-24 EP disclosed
EP-1539098-A2 COSMETIC COMPOSITION CONTAINING MICROCRYSTALLINE CELLULOSE FMC CORPORATION (US) 2005-06-15 EP disclosed
WO-2004026263-A2 COSMETIC COMPOSITION CONTAINING MICROCRYSTALLINE CELLULOSE FMC CORPORATION (US) 2004-04-01 WO disclosed