⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12954786 | 0.88 | THRB (0.40) | — | |
| SCHEMBL6864001 | 0.82 | — | — | |
| SCHEMBL293669 | 0.80 | — | — | |
| SCHEMBL984869 | 0.78 | — | — | |
| SCHEMBL10049904 | 0.78 | — | — | |
| SCHEMBL1780286 | 0.78 | — | — | |
| SCHEMBL24884612 | 0.78 | THRB (0.39) | — | |
| SCHEMBL294897 | 0.77 | ALDH1A1 (0.41) | — | |
| SCHEMBL12646124 | 0.76 | THRB (0.50) | — | |
| SCHEMBL6889406 | 0.76 | THRB (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240317753-A9 | Tricyclic heterocycles | MERCK PATENT GMBH (DE) | 2024-09-26 | — | — | US | claimed |
| US-20230174538-A1 | Tricyclic heterocycles | MERCK PATENT GMBH (DE) | 2023-06-08 | — | — | US | claimed |
| EP-0389189-B1 | Diazepine antiallergy agents | PFIZER LTD (GB) | 1994-05-18 | — | — | EP | claimed |
| US-5008263-A | Platelet activating factor antagonists; antiallergens; antiinflammatory agents | PFIZER INC. (US) | 1991-04-16 | — | — | US | claimed |
| EP-0389189-A2 | Diazepine antiallergy agents | Pfizer Limited (GB) | 1990-09-26 | — | — | EP | claimed |
| US-20260049080-A1 | WILD TYPE KIT INHIBITORS | BLUEPRINT MEDICINES CORP (US) | 2026-02-19 | — | — | US | disclosed |
| EP-4673111-A1 | COLORANT COMPOSITION FOR DYEING KERATIN FIBERS AND DYE KIT CONTAINING THE SAME | L'OREAL (FR) | 2026-01-07 | — | — | EP | disclosed |
| US-12448379-B2 | Wild type kit inhibitors | BLUEPRINT MEDICINES CORPORATION (US) | 2025-10-21 | — | — | US | disclosed |
| US-12297190-B2 | Modulators of STING (stimulator of interferon genes) | PFIZER INC. (US) | 2025-05-13 | — | — | US | disclosed |
| US-20240317753-A9 | Tricyclic heterocycles | MERCK PATENT GMBH (DE) | 2024-09-26 | — | — | US | disclosed |
| WO-2024178538-A1 | COLORANT COMPOSITION FOR DYEING KERATIN FIBERS AND DYE KIT CONTAINING THE SAME | L'OREAL (FR) | 2024-09-06 | — | — | WO | disclosed |
| US-20240262826-A1 | WILD TYPE KIT INHIBITORS | BLUEPRINT MEDICINES CORPORATION | 2024-08-08 | — | — | US | disclosed |
| WO-2002069918-A1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |
| US-6361571-B1 | USING TAUTOMERIC NONOXIDATIVE DYES AND POLYMETHINE DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-26 | — | — | US | disclosed |
| EP-1033965-A2 | AGENTS AND METHOD FOR PRODUCING SEMI-PERMANENT COLORATIONS OF KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999059529-A2 | AGENTS AND METHOD FOR PRODUCING SEMI-PERMANENT COLORATIONS OF KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |
| EP-0389189-B1 | Diazepine antiallergy agents | PFIZER LTD (GB) | 1994-05-18 | — | — | EP | disclosed |
| US-5008263-A | Platelet activating factor antagonists; antiallergens; antiinflammatory agents | PFIZER INC. (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0389189-A2 | Diazepine antiallergy agents | Pfizer Limited (GB) | 1990-09-26 | — | — | EP | disclosed |
| CN-1041943-A | Pyrrolo-[3,2-e] pyrazolo [1,5-a] pyrimidine derivatives and contain the medicine of above-mentioned composition | POLA CHEM IND INC (JP) | 1990-05-09 | — | — | CN | disclosed |