Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15253486 | 0.82 | THRB (0.36) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL36216 | 0.82 | THRB (0.36) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL5443893 | 0.75 | TSHR (0.39) | THRBTSHRALDH1A1 | |
| SCHEMBL5447282 | 0.74 | TSHR (0.41) | THRBTSHRALDH1A1 | |
| SCHEMBL1535500 | 0.69 | THRB (0.38) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL16027798 | 0.69 | THRB (0.31) | THRBTSHRALDH1A1 | |
| SCHEMBL25433904 | 0.68 | THRB (0.35) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL1005227 | 0.68 | ALDH1A1 (0.36) | THRBTSHRALDH1A1 | |
| SCHEMBL1535484 | 0.68 | THRB (0.35) | THRBTSHRALDH1A1 | |
| SCHEMBL3989228 | 0.68 | THRB (0.34) | THRBTSHRALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552380-B1 | POLYMERIZABLE ISOCYANURATE MONOMERS AND DENTAL COMPOSITIONS | 3M INNOVATIVE PROPERTIES CO (US) | 2019-04-24 | — | — | EP | disclosed |
| US-9237990-B2 | Polymerizable isocyanurate monomers and dental compositions | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-01-19 | — | — | US | disclosed |
| EP-2552380-A2 | POLYMERIZABLE ISOCYANURATE MONOMERS AND DENTAL COMPOSITIONS | 3M Innovative Properties Company (US) | 2013-02-06 | — | — | EP | disclosed |
| US-20130012614-A1 | POLYMERIZABLE ISOCYANURATE MONOMERS AND DENTAL COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-01-10 | — | — | US | disclosed |
| WO-2011126647-A2 | POLYMERIZABLE ISOCYANURATE MONOMERS AND DENTAL COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012614-A1 | POLYMERIZABLE ISOCYANURATE MONOMERS AND DENTAL COMPOSITIONS | ETV6, PCMT1, MLLT1 | THRB 3087/4885TSHR 3572/4885ALDH1A1 1402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.