Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737358 | 0.78 | AGBL2 (0.32) | PANK3 | |
| SCHEMBL12041152 | 0.77 | CCR1 (0.35) | PANK3 | |
| SCHEMBL14225108 | 0.77 | S1PR1 (0.33) | PANK3 | |
| SCHEMBL12414696 | 0.75 | S1PR1 (0.37) | — | |
| SCHEMBL12186132 | 0.75 | S1PR3 (0.43) | — | |
| SCHEMBL31188331 | 0.75 | MEN1 (0.33) | PANK3 | |
| SCHEMBL21736794 | 0.75 | TET2 (0.33) | PANK3 | |
| SCHEMBL11922548 | 0.75 | RPS6KA3 (0.33) | PANK3 | |
| SCHEMBL12190777 | 0.73 | NPC1 (0.37) | — | |
| SCHEMBL21105492 | 0.72 | PANK3 (0.38) | PANK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159532-A1 | PARATHYROID HORMONE (PTH) RECEPTOR ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159532-A1 | PARATHYROID HORMONE (PTH) RECEPTOR ANTAGONISTS AND USES THEREOF | PTH1R, CALCR, VDR | TRPV4 328/4885PANK3 1700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.