Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | NSD2 | O96028 | 4/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25555463 | 0.88 | NSD2 (0.33) | PRKDCSCN9ANSD2 | |
| SCHEMBL28989168 | 0.87 | NSD2 (0.34) | PRKDCSCN9ANSD2 | |
| SCHEMBL30257383 | 0.87 | NSD2 (0.34) | PRKDCSCN9ANSD2 | |
| SCHEMBL25555468 | 0.86 | NSD2 (0.33) | SCN9ANSD2 | |
| SCHEMBL25555426 | 0.86 | NSD2 (0.35) | NSD2GRM5 | |
| SCHEMBL30257068 | 0.86 | TGFBR1 (0.38) | PRKDCNSD2GRM5 | |
| SCHEMBL30257365 | 0.86 | CYP11B1 (0.36) | SCN9ANSD2 | |
| SCHEMBL25554961 | 0.86 | TGFBR1 (0.38) | PRKDCNSD2GRM5 | |
| SCHEMBL25555472 | 0.86 | CYP11B1 (0.36) | SCN9ANSD2 | |
| SCHEMBL30256984 | 0.86 | NSD2 (0.34) | PRKDCSCN9ANSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167073-A1 | ARYL OR HETEROARYL DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2023-06-01 | — | — | US | disclosed |
| US-20230167073-A1 | ARYL OR HETEROARYL DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167073-A1 | ARYL OR HETEROARYL DERIVATIVE | ARRB1, NR3C2, TRPC6 | GAA 4726/4885PRKDC 3935/4885SCN9A 760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.