Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | QPCT | Q16769 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159024 | 0.84 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3XDHAPP | |
| SCHEMBL15041085 | 0.83 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3XDHAPP | |
| SCHEMBL15034717 | 0.82 | XDH (0.49) | SLC6A2SLC6A4SLC6A3XDHAPP | |
| Hydrochloric Acid SCHEMBL161578 | 0.81 | XDH (0.48) | SLC6A2SLC6A4SLC6A3XDHAPP | |
| SCHEMBL161492 | 0.81 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3XDHAPP | |
| SCHEMBL163959 | 0.79 | ALDH1A1 (0.52) | SLC6A2SLC6A4SLC6A3CPT1AMAPT | |
| SCHEMBL161813 | 0.79 | CPT1A (0.42) | SLC6A2SLC6A4SLC6A3XDHAPP | |
| SCHEMBL159937 | 0.78 | CPT1A (0.44) | SLC6A2SLC6A4SLC6A3XDHAPP | |
| SCHEMBL163919 | 0.77 | SMN1; SMN2 (0.48) | SLC6A2SLC6A4SLC6A3CPT1ATRPV1 | |
| SCHEMBL170964 | 0.77 | XDH (0.44) | SLC6A2SLC6A4SLC6A3XDHAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012029032-A2 | HETEROCYCLIC COMPOUNDS AS DGAT1 INHIBITORS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2012-03-08 | — | — | WO | disclosed |