Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20216199 | 0.75 | HRH3 (0.43) | SMN1; SMN2KDM4EAPPHRH3LMNA | |
| SCHEMBL13761773 | 0.73 | NQO1 (0.58) | SMN1; SMN2KDM4EAPPKIF11LMNA | |
| SCHEMBL8099447 | 0.73 | SMN1; SMN2 (0.41) | SMN1; SMN2KDM4EAPPHRH3LMNA | |
| SCHEMBL17830938 | 0.71 | CYP2D6 (0.56) | KDM4EHRH3CYP3A4CYP2D6TP53 | |
| SCHEMBL678078 | 0.71 | CYP2D6 (0.56) | KDM4EHRH3CYP3A4CYP2D6TP53 | |
| SCHEMBL29053334 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4EAPPHRH3LMNA | |
| SCHEMBL13165304 | 0.71 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4EAPPHRH3LMNA | |
| SCHEMBL25557802 | 0.70 | RARB (0.58) | KDM4EHRH3L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL9158885 | 0.69 | LTA4H (0.40) | RAB9A | |
| SCHEMBL12083017 | 0.69 | PPARD (0.47) | LMNAATML3MBTL1MAOBAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159591-A1 | ECHINOCANDIN ANALOGUES AND PREPARATION METHOD THEREFOR | SHANGHAI SHENGDI PHARMACEUTICAL CO., LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20230159591-A1 | ECHINOCANDIN ANALOGUES AND PREPARATION METHOD THEREFOR | SHANGHAI SHENGDI PHARMACEUTICAL CO., LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159591-A1 | ECHINOCANDIN ANALOGUES AND PREPARATION METHOD THEREFOR | ERG28, CYP51A1, WEE1 | SMN1; SMN2 4214/4885KDM4E 4016/4885APP 2911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.