Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554705 | 0.88 | BACE1 (0.59) | BACE1 | |
| SCHEMBL4321083 | 0.87 | BACE1 (0.84) | BACE1 | |
| SCHEMBL4309954 | 0.87 | BACE1 (0.70) | BACE1 | |
| SCHEMBL1170658 | 0.87 | BACE1 (0.84) | BACE1 | |
| SCHEMBL1171281 | 0.87 | BACE1 (0.70) | BACE1 | |
| SCHEMBL2555793 | 0.83 | BACE1 (0.57) | BACE1 | |
| SCHEMBL2553934 | 0.83 | BACE1 (0.57) | BACE1 | |
| SCHEMBL12293372 | 0.83 | BACE1 (0.57) | BACE1 | |
| Hydrochloric Acid SCHEMBL2492580 | 0.82 | BACE1 (0.56) | BACE1 | |
| SCHEMBL2556967 | 0.81 | BACE1 (0.58) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556076-A2 | NOVEL SULTAM COMPOUNDS | Pfizer Inc. (US) | 2013-02-13 | — | — | EP | claimed |
| WO-2011125006-A2 | NOVEL SULTAM COMPOUNDS | PFIZER INC. (US) | 2011-10-13 | — | — | WO | claimed |
| US-20130150376-A1 | Novel Sultam Compounds | PFIZER INC. (US) | 2013-06-13 | — | — | US | disclosed |
| EP-2556076-A2 | NOVEL SULTAM COMPOUNDS | Pfizer Inc. (US) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011125006-A2 | NOVEL SULTAM COMPOUNDS | PFIZER INC. (US) | 2011-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150376-A1 | Novel Sultam Compounds | SULT2A1, SULT1A1, SULT1E1 | BACE1 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.