Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 9/20 | 0.64 |
| ▸ | ROCK1 | Q13464 | 9/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | JAK2 | O60674 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | JAK1 | P23458 | 2/20 | 0.55 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555842 | 1.00 | ROCK2 (0.64) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| SCHEMBL20661258 | 0.86 | ROCK2 (0.59) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| SCHEMBL14863508 | 0.85 | ROCK2 (0.62) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| SCHEMBL20661185 | 0.85 | ROCK2 (0.62) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| SCHEMBL14863507 | 0.85 | ROCK2 (0.62) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| SCHEMBL23429984 | 0.85 | ROCK2 (0.64) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| SCHEMBL19699462 | 0.84 | ROCK2 (0.71) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| SCHEMBL23429978 | 0.83 | ROCK2 (0.62) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| SCHEMBL20661259 | 0.82 | ROCK2 (0.58) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| SCHEMBL20661200 | 0.82 | ROCK2 (0.59) | ROCK2ROCK1NPC1RAB9AJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |