Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | CCR6 | P51684 | 2/20 | 0.64 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.64 |
| ▸ | NSD2 | O96028 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12833654 | 0.83 | MAPT (0.65) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL28715336 | 0.83 | MAPK1 (0.58) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL14765070 | 0.82 | CYP1A2 (0.77) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL29506228 | 0.82 | CYP1A2 (0.77) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL13546135 | 0.80 | MAPK1 (0.55) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL14765018 | 0.80 | CYP1A2 (0.58) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL12279541 | 0.78 | KMT2A (0.56) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL8285451 | 0.78 | MAPT (1.00) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL1520566 | 0.78 | APAF1 (0.65) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL28713484 | 0.78 | CYP1A2 (0.53) | MEN1KMT2AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130102650-A1 | ANTIMICROBIAL COMPOUNDS OF 1,4-NAPHTOQUINONE STRUCTURE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2013-04-25 | — | — | US | disclosed |
| US-20130102650-A1 | ANTIMICROBIAL COMPOUNDS OF 1,4-NAPHTOQUINONE STRUCTURE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2013-04-25 | — | — | US | disclosed |
| US-20130102650-A1 | ANTIMICROBIAL COMPOUNDS OF 1,4-NAPHTOQUINONE STRUCTURE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2013-04-25 | — | — | US | disclosed |
| EP-2555764-A1 | ANTIMICROBIAL COMPOUNDS OF 1,4- NAPHTOQUINONE STRUCTURE | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011124697-A1 | ANTIMICROBIAL COMPOUNDS OF 1,4- NAPHTOQUINONE STRUCTURE | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-10-13 | — | — | WO | disclosed |
| WO-2011124697-A1 | ANTIMICROBIAL COMPOUNDS OF 1,4- NAPHTOQUINONE STRUCTURE | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102650-A1 | ANTIMICROBIAL COMPOUNDS OF 1,4-NAPHTOQUINONE STRUCTURE | NR4A1, NR0B1, CBR1 | MEN1 4517/4885KMT2A 3812/4885MAPT 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.