Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | CDK1 | P06493 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxane SCHEMBL29281108 | 0.91 | TDP1 (0.63) | TDP1SMN1; SMN2CDK1ALDH1A1MAPK1 | |
| Tetrahydrofuran SCHEMBL29281107 | 0.89 | TDP1 (0.60) | TDP1SMN1; SMN2CDK1ALDH1A1MAPK1 | |
| SCHEMBL29281112 | 0.89 | TDP1 (0.60) | TDP1SMN1; SMN2CDK1ALDH1A1MAPK1 | |
| Ethyl Acetate SCHEMBL29281111 | 0.89 | TDP1 (0.71) | TDP1SMN1; SMN2CDK1ALDH1A1MAPK1 | |
| SCHEMBL1493992 | 0.88 | MAPK1 (0.57) | TDP1SMN1; SMN2CDK1ALDH1A1MAPK1 | |
| Butyric Acid SCHEMBL29281109 | 0.88 | TDP1 (0.66) | TDP1SMN1; SMN2CDK1ALDH1A1MAPK1 | |
| SCHEMBL7411536 | 0.87 | TDP1 (0.69) | TDP1SMN1; SMN2CDK1ALDH1A1MAPK1 | |
| SCHEMBL7000701 | 0.87 | SMN1; SMN2 (0.64) | TDP1SMN1; SMN2CDK1ALDH1A1MAPK1 | |
| SCHEMBL1162352 | 0.87 | TDP1 (0.56) | TDP1SMN1; SMN2CDK1ALDH1A1MAPK1 | |
| 3-Methylbutanoic Acid SCHEMBL29281110 | 0.87 | TDP1 (0.61) | TDP1SMN1; SMN2CDK1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119822987-A | Preparation method of 4-acetamido-5-chloro-2-methoxybenzoic acid methyl ester | 苏州诚和医药化学有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-117945941-A | Preparation method of 2-methoxy-4-acetamido-5-iodobenzoic acid methyl ester | 苏州诚和医药化学有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117843520-A | Methoxychlor-pram intermediate and preparation method and application thereof | 常熟泓德生物科技有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-113233992-A | Preparation method of 5-chloro-4-acetamido-2-methoxybenzoic acid methyl ester | 江苏巨莱生物医药有限公司 | 2021-08-10 | — | — | CN | claimed |
| CN-105523952-A | Preparation method of methyl 4-acetamido-5-chloro-2-methoxybenzoate | JINAN CHENGHUI SHUANGDA CHEMICAL CO LTD | 2016-04-27 | — | — | CN | claimed |
| EP-0047207-B1 | N-(1-ALLYL-2-PYRROLIDINYL-METHYL)-2-METHOXY-4-AMINO-5-METHYL-SULFAMOYL BENZAMIDE, PROCESS FOR ITS PREPARATION AND ITS USE AS A MEDICINE | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1985-02-20 | — | — | EP | claimed |
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| CN-119822987-B | Preparation method of 4-acetamido-5-chloro-2-methoxybenzoic acid methyl ester | 苏州诚和医药化学有限公司 | 2026-03-24 | — | — | CN | disclosed |
| CN-120208805-A | Metoclopramide Process for the preparation of intermediates | 华仁医学研究(安徽)有限公司 | 2025-06-27 | — | — | CN | disclosed |
| CN-119909010-A | Methoxychlor hydrochloride injection and preparation method thereof | 江西科为制药有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-119822987-A | Preparation method of 4-acetamido-5-chloro-2-methoxybenzoic acid methyl ester | 苏州诚和医药化学有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-119822987-A | Preparation method of 4-acetamido-5-chloro-2-methoxybenzoic acid methyl ester | 苏州诚和医药化学有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-119504547-A | Amisulpride preparation method of the composition | 山东安弘制药有限公司 | 2025-02-25 | — | — | CN | disclosed |
| US-5869513-A | ANTIULCER AGENTS | G. D. SEARLE & CO. (US) | 1999-02-09 | — | — | US | disclosed |
| WO-1995029897-A1 | METHOD OF USING (H+/K+) ATPase INHIBITORS AS ANTIVIRAL AGENTS | G.D. SEARLE & CO. (US) | 1995-11-09 | — | — | WO | disclosed |
| EP-0204215-A1 | 2-[(1H-benzimidazol-2-ylsulfinyl)methyl]-benzenamines | G.D. Searle & Co. (US) | 1986-12-10 | — | — | EP | disclosed |
| US-4550179-A | TREATMENT OF MIGRAINES; ANTISEROTONINE, HYPOTENSIVE AGENTS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE FRANCE (FR) | 1985-10-29 | — | — | US | disclosed |
| US-4405636-A | HEADACHES | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE FRANCE (FR) | 1983-09-20 | — | — | US | disclosed |
| US-4138492-A | FOR TREATMENT OF GASTROINTESTINAL DISORDERS | ANPHAR, S.A. (ES) | 1979-02-06 | — | — | US | disclosed |
| US-4039672-A | EMESIS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1977-08-02 | — | — | US | disclosed |