Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | RORC | P51449 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555975 | 0.87 | TDP1 (0.73) | TDP1SMN1; SMN2CDK1ALDH1A1LMNA | |
| Butyric Acid SCHEMBL29281109 | 0.84 | TDP1 (0.66) | TDP1SMN1; SMN2CDK1ALDH1A1LMNA | |
| SCHEMBL29281112 | 0.82 | TDP1 (0.60) | TDP1SMN1; SMN2CDK1ALDH1A1LMNA | |
| Ethyl Acetate SCHEMBL29281111 | 0.80 | TDP1 (0.71) | TDP1SMN1; SMN2CDK1ALDH1A1LMNA | |
| Dioxane SCHEMBL29281108 | 0.79 | TDP1 (0.63) | TDP1SMN1; SMN2CDK1ALDH1A1LMNA | |
| SCHEMBL1162352 | 0.78 | TDP1 (0.56) | TDP1SMN1; SMN2CDK1ALDH1A1LMNA | |
| SCHEMBL8900742 | 0.77 | TDP1 (0.59) | TDP1SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL6671177 | 0.77 | HTT (0.58) | TDP1SMN1; SMN2ALDH1A1LMNAKDM4E | |
| Tetrahydrofuran SCHEMBL29281107 | 0.77 | TDP1 (0.60) | TDP1SMN1; SMN2CDK1ALDH1A1LMNA | |
| SCHEMBL1493992 | 0.76 | MAPK1 (0.57) | TDP1SMN1; SMN2CDK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843520-A | Methoxychlor-pram intermediate and preparation method and application thereof | 常熟泓德生物科技有限公司 | 2024-04-09 | — | — | CN | disclosed |