Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555975 | 0.89 | TDP1 (0.73) | TDP1SMN1; SMN2KMT2AMEN1MAPT | |
| Ethopabate SCHEMBL29625103 | 0.83 | TDP1 (1.00) | TDP1SMN1; SMN2KMT2AMEN1MAPT | |
| Ethopabate SCHEMBL540932 | 0.83 | TDP1 (1.00) | TDP1SMN1; SMN2KMT2AMEN1MAPT | |
| Butyric Acid SCHEMBL29281109 | 0.83 | TDP1 (0.66) | TDP1SMN1; SMN2KMT2AMEN1MAPT | |
| Ethopabate SCHEMBL28629644 | 0.82 | TDP1 (0.97) | TDP1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL29281112 | 0.82 | TDP1 (0.60) | TDP1SMN1; SMN2KMT2AMEN1MAPT | |
| Dioxane SCHEMBL29281108 | 0.81 | TDP1 (0.63) | TDP1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL7411536 | 0.80 | TDP1 (0.69) | TDP1SMN1; SMN2KMT2AMEN1CDK1 | |
| SCHEMBL21219501 | 0.80 | TDP1 (0.82) | TDP1SMN1; SMN2KMT2AMEN1MAPT | |
| 3-Methylbutanoic Acid SCHEMBL29281110 | 0.80 | TDP1 (0.61) | TDP1SMN1; SMN2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843520-A | Methoxychlor-pram intermediate and preparation method and application thereof | 常熟泓德生物科技有限公司 | 2024-04-09 | — | — | CN | disclosed |