Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 14/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 14/20 | 0.36 |
| ▸ | WNT1 | P04628 | 9/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.30 |
| ▸ | CLK3 | P49761 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24024593 | 0.83 | GSK3B (0.34) | GSK3BDYRK1AWNT1MGLL | |
| Hydrochloric Acid SCHEMBL28735083 | 0.73 | GSK3B (0.47) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL928582 | 0.73 | HTR2A (0.36) | GSK3BDYRK1AWNT1MGLLHTR2A | |
| SCHEMBL708722 | 0.73 | CHRNB2 (0.36) | GSK3BDYRK1AWNT1MGLLHTR2A | |
| SCHEMBL17687467 | 0.73 | GSK3B (0.36) | GSK3BDYRK1AWNT1MGLLHTR2A | |
| SCHEMBL107330 | 0.73 | HTR2A (0.36) | GSK3BDYRK1AWNT1HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL930044 | 0.71 | HTR2A (0.36) | GSK3BDYRK1AWNT1MGLLHTR2A | |
| SCHEMBL4479461 | 0.71 | HPGD (0.44) | — | |
| SCHEMBL15332561 | 0.71 | — | — | |
| SCHEMBL17788669 | 0.69 | GSK3B (0.35) | GSK3BDYRK1AWNT1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |