Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30370270 | 0.78 | TUBB4A (0.70) | HDAC3HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL25560329 | 0.78 | TUBB4A (0.70) | HDAC3HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL25560425 | 0.76 | HDAC1 (0.44) | HDAC3HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL25195142 | 0.74 | HDAC3 (0.60) | HDAC3HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL23761144 | 0.74 | HDAC8 (0.55) | HDAC3HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL7084615 | 0.72 | MAPT (0.52) | HDAC3HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL7084616 | 0.72 | MAPT (0.52) | HDAC3HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL12428094 | 0.72 | MAPT (0.54) | HDAC3HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL23761150 | 0.71 | CYP3A4 (0.55) | HDAC3HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL13055402 | 0.70 | CYP17A1 (0.59) | CYP17A1NAMPTPSMB8ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081312-A1 | SMALL MOLECULE INDUCERS OF AUTOPHAGY | Vir Biotechnology, Inc. (US) | 2023-05-11 | — | — | WO | disclosed |