Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117250 | 1.00 | EPHX1 (0.42) | EPHX1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL9205945 | 1.00 | EPHX1 (0.42) | EPHX1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL9213526 | 1.00 | EPHX1 (0.42) | EPHX1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL3840048 | 0.98 | LMNA (0.41) | EPHX1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL24353239 | 0.95 | EPHX1 (0.48) | EPHX1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL9541689 | 0.95 | EPHX1 (0.48) | EPHX1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL9204346 | 0.95 | EPHX1 (0.48) | EPHX1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL27800763 | 0.95 | EPHX1 (0.48) | EPHX1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL11699658 | 0.95 | EPHX1 (0.48) | EPHX1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL9208917 | 0.95 | EPHX1 (0.48) | EPHX1LMNACNR1ADRA1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086432-A1 | PRODRUGS OF NEUROSTEROID ANALOGS AND USES THEREOF | EMORY UNIVERSITY (US) | 2023-05-19 | — | — | WO | disclosed |