Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.61 |
| ▸ | RXRA | P19793 | 4/20 | 0.60 |
| ▸ | RXRB | P28702 | 4/20 | 0.60 |
| ▸ | RXRG | P48443 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | KMO | O15229 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.51 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.51 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30469525 | 1.00 | DHODH (0.61) | DHODHRXRARXRBRXRGSRD5A2 | |
| SCHEMBL177461 | 0.90 | RXRA (0.63) | DHODHRXRARXRBRXRGSRD5A2 | |
| SCHEMBL121358 | 0.90 | RXRA (0.69) | DHODHRXRARXRBRXRGSRD5A2 | |
| SCHEMBL30393660 | 0.90 | RXRA (0.63) | DHODHRXRARXRBRXRGSRD5A2 | |
| SCHEMBL26683019 | 0.89 | DHODH (0.57) | DHODHRXRARXRBRXRGSRD5A2 | |
| SCHEMBL8442426 | 0.88 | RXRA (0.71) | DHODHRXRARXRBRXRGSRD5A2 | |
| SCHEMBL17048588 | 0.86 | RXRA (0.72) | DHODHRXRARXRBRXRGSRD5A2 | |
| SCHEMBL2559790 | 0.85 | TRIM24 (0.60) | DHODHRXRARXRBRXRGSRD5A2 | |
| SCHEMBL29784281 | 0.85 | RXRA (0.72) | DHODHRXRARXRBRXRGSRD5A2 | |
| SCHEMBL2344585 | 0.85 | RXRA (0.72) | DHODHRXRARXRBRXRGSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814332-B1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-07 | — | — | EP | disclosed |