Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.72 |
| ▸ | RXRB | P28702 | 4/20 | 0.72 |
| ▸ | RXRG | P48443 | 3/20 | 0.72 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | KIF11 | P52732 | 1/20 | 0.59 |
| ▸ | DHODH | Q02127 | 1/20 | 0.58 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.56 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.56 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CFTR | P13569 | 1/20 | 0.54 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.54 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2344585 | 1.00 | RXRA (0.72) | RXRARXRBRXRGSRD5A2MEN1 | |
| SCHEMBL30393660 | 0.88 | RXRA (0.63) | RXRARXRBRXRGSRD5A2MEN1 | |
| SCHEMBL177461 | 0.88 | RXRA (0.63) | RXRARXRBRXRGSRD5A2MEN1 | |
| SCHEMBL4618676 | 0.86 | SRD5A2 (0.70) | RXRARXRBRXRGSRD5A2MEN1 | |
| SCHEMBL2984165 | 0.85 | KIF11 (0.58) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL30469525 | 0.85 | DHODH (0.61) | RXRARXRBRXRGSRD5A2MEN1 | |
| SCHEMBL25560577 | 0.85 | DHODH (0.61) | RXRARXRBRXRGSRD5A2MEN1 | |
| SCHEMBL14149921 | 0.84 | NPC1 (0.62) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL23698041 | 0.84 | RXRA (1.00) | RXRARXRBRXRGSRD5A2DHODH | |
| SCHEMBL24106776 | 0.83 | KIF11 (0.67) | ALDH1A1KIF11PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179046-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC | 2025-06-05 | — | — | US | disclosed |
| CN-113631548-B | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2023-06-06 | — | — | CN | disclosed |
| US-11390610-B2 | Piperazine derivatives as MAGL inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2022-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179046-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | HTR2B, HTR1B, HTR5A | RXRA 3714/4885RXRB 2415/4885RXRG 3723/4885 |
| US-11390610-B2 | Piperazine derivatives as MAGL inhibitors | MAGI3, PYM1, MAG | RXRA 4515/4885RXRB 4498/4885RXRG 4575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.