Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 4/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954245 | 1.00 | NR4A2 (0.60) | NR4A2MAOBMAOAMAPTTP53 | |
| SCHEMBL7170719 | 0.86 | NR4A2 (0.71) | NR4A2MAOBMAOAMAPTTP53 | |
| SCHEMBL21763 | 0.83 | NR4A2 (0.59) | NR4A2MAOBMAOAMAPTTP53 | |
| SCHEMBL29663864 | 0.83 | NR4A2 (0.59) | NR4A2MAOBMAOAMAPTTP53 | |
| SCHEMBL3618405 | 0.82 | MAPT (0.70) | NR4A2MAOBMAOAMAPTTP53 | |
| SCHEMBL12539076 | 0.81 | NR4A2 (0.41) | NR4A2MAOBMAOAMAPTTP53 | |
| SCHEMBL2559738 | 0.81 | SMN1; SMN2 (0.57) | NR4A2MAOBMAOAMEN1KMT2A | |
| SCHEMBL2562346 | 0.81 | NR4A2 (0.62) | NR4A2MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL29950561 | 0.80 | MAOB (0.60) | MAOBKMT2ACA1CA2 | |
| SCHEMBL3761511 | 0.80 | MAOB (0.59) | MAOBNPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |