Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25562062 | 0.72 | BRD4 (0.37) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL68581 | 0.71 | MEN1 (0.61) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7255005 | 0.71 | BRD4 (0.44) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL6641189 | 0.70 | MAPT (0.34) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL5512697 | 0.70 | MEN1 (0.59) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL29473284 | 0.70 | MEN1 (0.59) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL7142299 | 0.70 | MEN1 (0.59) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| Lactic Acid SCHEMBL30205441 | 0.69 | MEN1 (0.50) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL30205268 | 0.68 | MEN1 (0.58) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL19150148 | 0.68 | SRD5A2 (0.53) | MAPTMEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088420-A1 | 1H-BENZO[B]AZEPIN-2(3H)-ONE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER | Chengdu Anticancer Bioscience, Ltd. (CN) | 2023-05-25 | — | — | WO | disclosed |