Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20845443 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| SCHEMBL26559146 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| SCHEMBL25491031 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| SCHEMBL98089 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| SCHEMBL2228780 | 0.76 | SYK (0.40) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| SCHEMBL5306075 | 0.75 | ALDH1A1 (0.63) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| SCHEMBL578910 | 0.74 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| SCHEMBL1443873 | 0.73 | ALDH1A1 (0.70) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| SCHEMBL25491034 | 0.73 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| SCHEMBL2228612 | 0.73 | PDE2A (0.40) | ALDH1A1KDM4EMAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083919-A1 | CONJUGATES COMPRISING A PHOSPHORUS (V) AND A CAMPTOTHECIN MOIETY | TUBULIS GMBH (DE) | 2023-05-19 | — | — | WO | disclosed |
| WO-2023083900-A1 | CONJUGATES COMPRISING A PHOSPHORUS (V) AND A DRUG MOIETY | TUBULIS GMBH (DE) | 2023-05-19 | — | — | WO | disclosed |